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Stay informed about CLN2 disease resources and information as it becomes available at:


Click here to watch on-demand, a no-cost, live, educational webinar discussing the importance of early genetic testing in pediatric epilepsy - Insights from a CLN2 disease experience.

EU/CLN2/0783 Nov 2019

Parent holding child's hand

The Natural Course of CLN2 Disease is Rapid

Children with CLN2 disease commonly experience a complete loss of cognitive abilities, motor function and vision within the first decade of life.1,2

Child under magnifying glass

Earlier Diagnosis is Critical & Testing is Straightforward

Given the rapid rate of progression, early diagnosis is essential to ensure that families can benefit from CLN2-specific management strategies and maximise quality time.3,4

Doctor treating patient with stethoscope

Optimise Care With CLN2 Disease Management Strategies

Experts have identified CLN2 disease-specific management strategies that can greatly impact patient care and quality of life.4

1. Schulz A et al. NCL diseases – clinical perspectives. Biochimica et Biophysica Acta. 2013;1832:1801-1806. 2. Mole SE and Williams RE. Neuronal ceroid-lipofuscinoses. 2001 Oct 10 [Updated 2013 Aug 1]. In: Pagon RA, Adam MP, Ardinger HH et al. eds. GeneReviews® [internet]. Seattle, WA: University of Washington; 1993-2016. 3. Nickel M et al. Disease characteristics and progression in patients with late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease: an observational cohort study. Lancet Child Adolesc Health 2018;2(8):582–590. 4. Williams RE et al. Management Strategies for CLN2 Disease. Pediatr Neurol 2017;69:102–112.